Marijuana may help with sleep by acting on the endocannabinoid system, a network of receptors in the brain and body that plays a role in regulating sleep and other functions. Cannabis contains compounds called cannabinoids, which can interact with these receptors and produce various effects.
One of the main cannabinoids in marijuana is THC (tetrahydrocannabinol), which is known to have sedative effects and may help to improve sleep. THC is thought to bind to cannabinoid receptors in the brain and body, leading to changes in the activity of certain neurotransmitters and other signaling molecules. This can affect the sleep-wake cycle, relaxation, and other processes that are important for sleep.
CBD (cannabidiol) is another cannabinoid found in cannabis and hemp plants. It is a non-psychoactive compound, meaning that it does not produce the “high” or psychoactive effects that are typically associated with THC (tetrahydrocannabinol), another cannabinoid found in cannabis.
There is some evidence to suggest that CBD may be helpful for improving sleep. CBD is thought to act on the endocannabinoid system, a network of receptors in the brain and body that plays a role in regulating sleep and other functions. It is believed to interact with cannabinoid receptors in the body and brain, leading to changes in the activity of certain neurotransmitters and other signaling molecules. This may help to improve sleep by promoting relaxation and reducing stress and anxiety.
It’s important to note that the effects of marijuana on sleep can vary widely from person to person, and not everyone will experience the same benefits or risks. Some people may find that marijuana helps them fall asleep more easily or improves the quality of their sleep, while others may find that it disrupts their sleep or causes other side effects.
ข้อมูลอ้างอิง (บางส่วน)
- Babson, K. A., Sottile, J., & Morabito, D. (2017). Cannabis, cannabinoids, and Sleep: A Review of the Literature. Current Psychiatry Reports, 19(4), 23. https://doi.org/10.1007/s11920-017-0775-9
- Belendiuk, K. A., Babson, K. A., Vandrey, R., & Bonn-Miller, M. O. (2015). Cannabis species and cannabinoid concentration preference among sleep-disturbed medicinal cannabis users. Addictive Behaviors, 50, 178-181. https://doi.org/10.1016/j.addbeh.2015.06.032
- Bhagavan, C., Kung, S., Doppen, M., John, M., Vakalalabure, I., Oldfield, K., Braithwaite, I., & Newton-Howes, G. (2020). cannabinoids in the Treatment of Insomnia Disorder: A Systematic Review and Meta-Analysis. CNS Drugs, 34(12), 1217-1228. https://doi.org/10.1007/s40263-020-00773-x
- Bisogno, T., Hanuš, L., De Petrocellis, L., Tchilibon, S., Ponde, D. E., Brandi, I., Moriello, A. S., Davis, J. B., Mechoulam, R., & Di Marzo, V. (2001). Molecular targets for cannabidiol and its synthetic analogues: Effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of Anandamide. British Journal of Pharmacology, 134(4), 845-852. https://doi.org/10.1038/sj.bjp.0704327
- Bonn-Miller, M. O., Babson, K. A., Vujanovic, A. A., & Feldner, M. T. (2010). Sleep Problems and PTSD Symptoms Interact to Predict Marijuana Use Coping Motives: A Preliminary Investigation. Journal of Dual Diagnosis, 6(2), 111-122. https://doi.org/10.1080/15504261003751887
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